Microdosing

April 18, 2024 Lynne Nardizzi

Here’s a guide to the latest research on microdosing.

Can Microdosing Hurt the Heart?

February 2, 2024 Lynne Nardizzi

Psychedelics like psilocybin, MDMA, LSD, and DMT act on serotonin receptors, and previous research has found that other drugs that act on serotonin receptors can cause fibrosis, or the thickening of heart valves.

That, in turn, can lead to serious or even fatal heart issues like arrhythmias or valvular heart disease.

So far, there’s been little research on the link between repeated psychedelics use and heart health, but this week, researchers at the University of Fribourg Center for Psychiatric Research in Switzerland published a paper in the Journal of Psychopharmacology reviewing the existing evidence.

“It is possible that chronic microdosing may carry a risk of fibrosis and valvular heart disease, which should be assessed in future studies,” the authors write.

“Any future work considering longer microdosing regimens should incorporate breaks and regular screening for vascular abnormalities.”

Microdosing and Authenticity

July 11, 2023 Lynne Nardizzi

A recent study found that on the microdosing day and the day thereafter, state authenticity was significantly higher.

Furthermore, the number of activities and the satisfaction with them were higher on the day when participants microdosed, while the following day only the number of activities was higher.

The researchers propose that feeling and behaving authentically could have a central role in explaining the positive effects of microdosing on health and wellbeing that are reported by their study.

Microdosing Mushrooms? Results Are Still Mixed.

July 2, 2023 Lynne Nardizzi

Microdosing psychedelics has benefits, users say. Science isn’t convinced.

Some people microdose for better mental health, or personal and spiritual growth. Scientific evidence for microdosing, though, is scarce and has been mixed.

Psilocybin and Lyme Disease?

May 19, 2023 Lynne Nardizzi

Psilocybin is both serotonergic and anti-inflammatory and therefore may offer significant therapeutic benefits to patients with mental illness secondary to autoimmune inflammation.

This study suggests that the role of microdosed psilocybin in the treatment of neuropsychiatric Lyme disease and autoimmune encephalopathies warrants further study.

Microdosing LSD - No Long-term Changes Found

May 2, 2023 Lynne Nardizzi

A new study on microdosing LSD did not find any beneficial long-term changes in mood or cognition.

Microdosing, Setting, and Does it Work?

April 14, 2023 Lynne Nardizzi

The research on benefits and long-term effects of microdosing continues to be mixed.

More on Microdosing

September 26, 2022 Lynne Nardizzi

There is still no definitive evidence that microdosing with psychedelics is either effective or safe. Keep reading to read the potential benefits and risks.

Microdosing- Panacea or Placebo?

August 31, 2022 Lynne Nardizzi

Is it all hype or is there genuine hope for therapeutic application of microdosing?

There’s certainly plenty of ‘conflicting’ information or results available from studies of different methodologies. Here, we begin with an overview of what microdosing is, who does it, and for what purposes. We then review available evidence and summarize benefits and risks of microdosing. Finally, we get more practical and discuss microdosing regimens, measurement of accurate dosing, and ‘set and setting’ consideration to microdosing.